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Unlike the effectiveness only given before injury (prophylactic effect) of the standard cytoprotective agents (for review, see, i.e., [10,11]), BPC 157, in addition to its prophylactic effect, has a strong curative effect given even much later after injury induction, during ischemia as well as during reperfusion (for review, see, i.e., [2,3,4,5,6,7,8])

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While necessary for acute survival, this response generates an enormous quantity of reactive oxygen species (ROS) as collateral damage