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These complexes are delivered to ferritin via the ferric iron molecular chaperone poly(C)-binding protein 1 (PCBP1), exacerbating labile iron availability and ferroptosis progression
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Therefore, regulating tumour progression hinges on maintaining ROS below the critical threshold that supports oncogene dependence [23], on the basis of which targeted regulation of SOD activity is regarded as a potential strategy in cancer treatment [24]
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