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[1] [2] Then the peroxidic reaction: 3) Compound I + electron donor → Compound II (Porphyrin- -Fe IV =OH) + oxidized donor 4) Compound II + electron donor → catalase-peroxidase (Porphyrin-Fe III ) + oxidized donor which requires the addition of alternative electron donor (other than hydrogen peroxide) to return the enzyme to first a second intermediate, Compound II, then its active state in low hydrogen peroxide conditions

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Identification and functional characterization of a novel, tissue-specific… [PMID: 10601238] Laboratory literature summary: Identification and functional characterization of a novel, tissue-specific NAD(+)-dependent isocitrate dehydrogenase beta subunit isoform