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While we wait for the adequately powered randomized controlled trials to be run, we cannot let “perfect be the enemy of good.” For the person living with PV or MPNs today, the most effective “drug” may well be a pair of walking or running shoes, provided they are used within a framework of clinical safety and individualization

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Phillips says all he can find is one small safety study from a decade ago, and a trial that only started enrolling participants this past February