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This controlled inflammation leads to: Increased fibroblast activity Enhanced collagen deposition Strengthening of the weakened ligaments Improved joint stability and function Unlike steroid injections, which suppress inflammation and may degrade tissue over time, prolotherapy seeks to stimulate tissue regeneration
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101–103 However, it is incapable of increasing sGC’s activity by more than 2–3-fold – explaining why it cannot produce profound hypotension the way that NO overdoses can
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