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A thorough analysis of the mechanism of action and adverse effects linked with the first-generation drug has enabled the rectification of these issues in the development of subsequent agents
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An imbalance in glutathione metabolism, defined by lower GSH:GSSG, has been linked to a number of chronic diseases including feline chronic renal failure (43) and in humans, cancer, neurodegenerative disorders, cystic fibrosis, viral infection, diabetes mellitus, renal failure and liver disease (44)