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It was hypothesised that the organophosphates induce various abnormalities such as an elevated prevalence of lymphoproliferative disorders associated with impaired natural killer (NK) cell and cytotoxic T cell function

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In addition, due to the poor solubility of Qu in water, it cannot be fully dissolved in the dermis even loaded in normal MSN or other nanoparticles [34,35], so traditional nano-delivery of Qu may not significantly increase the therapeutic effect on AGA [36]