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Several studies have produced strong evidence to support the idea that MTs function as zinc chaperones for the regulation of gene expression and activity of proteins, such as metalloproteins and metal-dependent transcription factors, as shown in Figure 2 and discussed in the following papers [79,80]

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Subsequent analysis verified that Epitalon exhibits epigenetic action by specifically binding to the CAG region of DNA, which serves as a methylation target for plant cytosine methyltransferases

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