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Yet, aside from two sequence features shared by all PIFs—an N-terminal active phyB-binding (APB) motif that confers phyB interaction and a C-terminal bHLH domain for DNA binding and oligomerization 37 , the sequence-function landscape of PIF4 remains largely unexplored

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In blood, pCG levels rise with declining renal function and pCG has been suggested as diagnostic and prognostic marker across CKD stages (Choudhary et al