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Regulation of CD4+ and CD8+ T Cell Biology by Short-Chain Fatty Acids and Its Relevance for Autoimmune Pathology
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For instance, Phe participates in classic substrate-driven negative feedback: when plasma Phe concentrations rise due to dietary intake or endogenous release, Phe acts as an activator of its own rate-limiting enzyme(PAH), thereby accelerating its metabolic conversion to Tyr (32)
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