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Following ubiquitination, receptor proteins such as sequestosome-1 (SQSTM1 or p62) bind to LC3-II via their LC3-interacting region (LIR) (Wang S
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Therefore, this (2Fe-2S-bridged dimers)-GSH complex is considered a redox sensor that could regulate oxidoreductase activity depending on the redox state of the cytosolic free glutathione pool [36]
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