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Further, in diazepam tolerance/withdrawal and physical dependence/withdrawal studies [58], BPC 157 coadministration in chronically treated diazepam mice counteracts diazepam tolerance and withdrawal, postpones physical dependence, and prolongs residual diazepam anticonvulsive activity [58]

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When administered to rodents, the compound caused a sustained decrease in daily food consumption and gradual weight loss over time, without causing hypoglycaemia (since amylin’s actions are insulin-dependent and do not override normal glucose regulation)