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However, their combined supplementation does not significantly impact the incidence of cardiovascular disease events, myocardial infarction, or cognitive decline

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However, 3T3-L1 preadipocytes treated with LA exhibit lower insulin-induced differentiation by modulating activity and/or expression of various anti-adipogenic transcription factors mainly through activating the MAPK pathways that negatively regulate PPARγ and C/EBPα [141]