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MRI-based biomarkers, such as T2 mapping and dGEMRIC, can identify early OA and assess repair quality over time, aiding both in patient selection and long-term monitoring (Zhang et al., 2023)
NAD+ Production
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Metformin, an AMP-activated protein kinase (AMPK) activator widely used in diabetes, is currently in phase I clinical trials for heart failure with preserved ejection fraction (HFpEF) (Tables 1 and 2)
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