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[DOI] [PMC free article] [PubMed] [Google Scholar] 49.Hung CM, Calejman CM, Sanchez-Gurmaches J, Li H, Clish CB, Hettmer S, Wagers AJ, Guertin DA

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Our previous investigation in porcine ischemia/reperfusion (I/R) models revealed hypoxia-associated damage, characterized by the overexpression of VEGF, iNOS, HIF-1α, and NOX2, leading to detectable high levels of O 2 • in retinal arterioles, ultimately causing endothelial dysfunction [307]