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An entirely separate candidate gene study involving 275 patients who had suffered acute liver failure after either deliberate or accidental APAP overdose also reported some borderline significant associations.68 For the rs1467558 CD44 variant discussed above, there was a trend towards significance in those who had overdosed unintentionally

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Multivitamin products typically contain lower doses (around the daily intake target), while single-nutrient vitamin B12 dietary supplements can range from 50 to 1,000 mcg