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As noted by the Alzheimer’s Drug Discovery Foundation (ADDF), the bulk of research involving epithalamin and epithalon has been conducted in Russia (or formerly, the Soviet Union) and has not been subject to independent confirmation [1]

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Interestingly, in animal models of glaucoma, the absence or downregulation of different glutamate transporters resulted in the death of RGCs, even in the absence of high IOP [170]