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In ovarian cancer, hypoxia results in CCL28 upregulation, leading to a robust increase in Treg infiltration, VEGF and blood vessels, whereas depletion of Tregs reduces intratumoral VEGF levels and tumor angiogenesis 18,81
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The benzyl alcohol inhibits microbial growth, allowing the solution to be used for multiple withdrawals from the same container — a critical requirement when reconstituting lyophilised peptides for serial laboratory experiments
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