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50 Local SDF-1α release increased the recruitment of systemically infused bone marrow-derived MSCs by 700% in a mouse model of myocardial infarction (MI), 51 suggesting that cartilage repair scaffolds releasing SDF-1α may perform synergistically with MSCs from marrow recruitment or intra-articular injections

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As supplements have been unable to fully address the current deficiencies in micronutrients, it is unlikely they will successfully ameliorate a future increased health burden caused by nutrient dilution in crops