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On the other hand, Mulcahy et al described a critical distal ARE element (ARE4), located ~ 3.1kb upstream of the transcriptional start site, which mediated constitutive and β-NF inducible expression in HepG2 cells (Mulcahy et al., 1997)
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In the CNS, CCL11 has been implicated in age-associated cognitive decline, psychiatric disorders, multiple sclerosis (MS), and Alzheimer’s disease (AD) (reviewed in: 27 )
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