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Further studies using knockout animals indicate that at least in rodents peroxiredoxin 2 and glutaredoxin 1 are the major enzymes detoxifying endogenous H 2 O 2 in RBC (Lee et al., 2003
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Normal dermal fibroblasts were seeded into a 96-well cell culture plate and have been grown to confluence in high glucose media, supplemented with 10% fetal calf serum for around 3 days
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