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BPC-157 compared against two rationally designed hybrid analogs, CIARA-1 and CIARA-2, each joining a BPC-157-derived fragment to an arginine-containing C-terminal sequence Reported finding All three compounds showed a competitive mechanism, with Michaelis-Menten constants rising while maximum velocity was unchanged
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NNMT expression increases significantly with obesity and aging, particularly in white adipose tissue and skeletal muscle
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