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Analytical platforms such as 1 H-NMR and liquid or gas chromatography coupled to mass spectrometry, in conjunction with chemometric and multivariate data analysis, allow the simultaneous determination and comparison of thousands of chemicals in biological fluids such as serum and urine, as well as the chemical constituents of cells and tissues

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“Structure of the Blood‐Brain Barrier and Its Role in the Transport of Amino Acids.” Journal of Nutrition 136: 218S–226S