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For example, some studies have suggested that there may be different variants of the genes encoding transketolase, which differ in their ability to bind the active form of thiamine, particularly at low thiamine concentrations
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The conjugation of GSH with dichloromethane results in the formation of highly unstable s-chloromethylglutathione adducts, containing an electrophilic center capable of modifying DNA [26,27], with subsequent toxic effects
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