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FOXM1 can regulate the expression of various genes, such as the cell cycle regulatory genes polo-like Kinase 1 (PLK1) and Centromere protein A (CENP-A) (18,29), DNA damage repair genes (Aurora kinase B, Baculoviral IAP Repeat-Containing Protein 5, BUB1 mitotic checkpoint serine/threonine kinase B, centromere protein E, Signal STAT3) (9) and apoptosis-associated genes growth Arrest-specific Transcripts (GAS5), TATA-Box Binding Protein Associated Factor 15 (TAF15) and stromal cell derived factor 4 (SDF4) (31)