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The enhanced permeability and retention (EPR) effect, which allows nanoparticles to accumulate within tumor tissues due to their leaky vasculature, can also be exploited by surfactant-based systems as well as receptor-mediated targeting [425]
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Folic acid inhibits COLO-205 colon cancer cell proliferation through activating the FRα/c-SRC/ERK1/2/NFκB/TP53 pathway: in vitro and in vivo studies
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