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Since 1998, Scott and colleagues have regarded ME/CFS as a stress-related disorder and proposed that HPA-axis hypofunction may reflect a state of stress-related hypocortisolism or reduced HPA-axis drive (Scott et al., 1998)

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Interestingly, the elimination half-life of BPC-157 is relatively short at less than 30 minutes, with intact peptide becoming undetectable after approximately four hours