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A blood test for SDMA (symmetric dimethylarginine), acts like an early warning system that the kidneys aren’t filtering the blood the way they should.[15] SDMA can detect as little as 25-40% reduction in kidney function, compared to 75% loss of kidney function for the creatinine test, for example.[16] The main concern with this newer test is that there haven’t been any large-scale studies in cats on its use