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Dose titration: start at the lowest clinical dose for month 1, titrate up through the first half of month 2, run the highest dose for the second half of month 2 and all of month 3
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Effect of oral semaglutide on the pharmacokinetics of thyroxine after dosing of levothyroxine and the influence of co-administered tablets on the pharmacokinetics of oral semaglutide in healthy subjects: an open-label, one-sequence crossover, single-center, multiple-dose, two-part trial