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Macrophages that are in close contact with fibroblasts can be regulated by receptor–ligand connections, such as interleukin (IL)-6 produced by fibroblasts, which induces inflammation, or Colony-Stimulating Factor 1 (CSF1) signaling that supports the survival of macrophages [73]
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While B12 injections raise B12 levels much more quickly than oral supplements, consistency is key to maintaining those benefits
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