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5 Discussion Cu homeostasis dysfunction and cuproptosis are closely correlated with the occurrence of some genetic, neurodegenerative, cardiovascular, tumoral diseases, and the medical options have been developed into recovering Cu homeostasis or triggering Cu dysfunction (Chen et al., 2022)

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solutions particularly those intended for ophthalmic use, can be formulated as 0.01% -10% isotonic solutions, pH about 5-7, with appropriate salts