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Each plate was subjected to high-content confocal microscopy to extract several image features from each channel, for each well (see Table S1 for a full list)

30count

Variants:1 Glow + 1 Sleep

In resistant cases, by comparison, two distinct failure modes emerge, in which either terminally exhausted T-cell clones prevail and exhibit restricted stem-like potential and epigenetic fixation into dysfunctional states that impair immediate effector function or the memory precursor pool contracts, leading to loss of long-term immune surveillance