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In contrast to our study, van der Woude et al[38] failed to demonstrate any changes in the expression of BAX, Bcl-2, and Bcl-xl between their study groups, which were similar to those in our study

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Because of mechanical changes present in disease states and in a developing embryo, further understanding of the relationship between cytokines, physical forces, and mechanotransducers will help researchers to determine how to either inhibit or promote angiogenesis to treat diseases or develop improved vascularization strategies for tissue engineering