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4.1.3 Regulation of KARs by channel blockers Positively charged polyamine molecules are ubiquitously present in bacterial, plant, and animal cells and frequently function as blockers of cation-selective ion channels (Tabor and Tabor, 1984)
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A decreased GSH–oxidized glutathione ratio that signals prolonged oxidative stress is consistently observed in ASD individuals, as reported by multiple meta-analyses [183,184,185,186]
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