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In 2 randomized controlled trials conducted by Xu et al, 24,25 the administration of vitamin B12 in varying forms in patients with postherpetic neuralgia and acute ophthalmic herpetic neuralgia sustainably and significantly decreased their pain severity for up to 1 year compared with controls receiving intramuscular injection of vitamin B12 and lidocaine

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KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease