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The decomposition of hydroperoxides releases several products such as acids, ketones and aldehydes

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324,325,326 Under the influence of Aβ, the expression of some MAM-related proteins, such as IP3Rs and VDAC1, is significantly increased, 325,327,328 leading to mitochondrial Ca 2+ overload, inhibition of normal ATP synthesis, and potential release of apoptotic signals